All of a sudden, I received this error at a costumer site. At first I was thinking that it was simply because the web site has stopped, or another IIS-related thing, but all everything was running. I even restarted the web site and the IIS service.

But, this was in fact related to framework, and the solution was simply to open a Command Prompt as Administrator and run the following command:

c:\WINDOWS\Microsoft.NET\Framework\v4.0.30319\aspnet_regiis.exe –iru

 

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The command finished in a matter of seconds, the error disappeared from Operations Manager right away and the web console worked fine again.

When the solution was that simple, I also created a recovery task for this one.